Publications

2024

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• Dutta D, Kanca O, Shridharan RV, Marcogliese PC, Steger B, Morimoto M, Frost FG, MacnamaraE, Undiagnosed Diseases Network, Wangler MF, Yamamoto S, Jenny A, Adams D, Malicdan MC, Bellen HJ (2024). Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development and viability. PNAS 121: e2322582121.

 

• Moulton MJ, Atala K, Zheng Y, Dutta D, Grange DK, Lin W, Wegner DJ, Wambach JA, Duker AL, Bober MB, Kratz L, Wise CA, Oxendine I, Khanshour A, Undiagnosed Diseases Network, Wangler MF, Yamamoto S, Cole FS, Rios J, Bellen HJ (2024). Dominant Missense Variants in SREBF2 are Associated with Dermatological, Neurological, and Skeletal Defects. Genetics in Medicine 6: 101174.

 

• Jenny Liao Z, Chung H, Shih C, Wong KKL, Dutta D, Nil Z, Burns CG, Kanca O, Park YJ, Zuo Z, Marcogliese PC, Sew K, Bellen HJ, Verheyen EM (2024). Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila. Nature Communications 15: 3326.

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2023

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• Dutta D, Kanca O, Byeon SK, Marcogliese PC, Zuo Z, Shridharan RV, Park JH, Undiagnosed Diseases Network, Lin G, Ge M, Heimer G, Kohler JN, Wheeler MT, Kaipparettu BA, Pandey A, Bellen HJ (2023). A defect in mitochondrial fatty acid synthesis impairs iron metabolism and causes elevated ceramide levels. Nature Metabolism 5: 1595-1614.

 

• Pan X, Dutta D, Liu L, Bellen HJ (2023). Sphingolipids in neurodegenerative diseases. Frontiers in Neuroscience 17: 1137893.

 

2022

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• Marcogliese PC*, Dutta D*, Sinha-Ray S, Dang NDP, Zuo Z, Wang Y, Lu D, Fazal F, Ravenscroft TA, Chung H, Kanca O, Wan JJ, Douine ED, Undiagnosed Diseases Network, Pena LDM, Yamamoto S, Nelson SF, Might M, Meyer KC, Yeo NC, Bellen HJ (2022). Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling. Science Advances 8: eabl5613. (*Co-first author) 

 

• Ray SS, Dutta D, Dennys C, Powers S, Roussel F, Lisowski P, Glazar P, Zhang X, Biswas P, Caporale JR, Rajewsky N, Bickle M, Wein N, Bellen HJ, Likhite S, Marcogliese PC, Meyer KC (2022) Mechanisms of IRF2BPL-related disorders and identification of a potential therapeutic strategy. Cell Reports 41: 111751.

 

• Kanca O, Zirin J, Hu Y, Tepe B, Dutta D, Lin W, Ma L, Ge M, Zuo Z, Liu L, Levis RW, Perrimon N, Bellen HJ (2022). An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR mediated homologous recombination. eLife 1: e76077.

 

2021

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• Dutta D, Sharma V, Mutsuddi M, Mukherjee A (2021). Regulation of Notch signaling by E3 ubiquitin ligases. The FEBS Journal 289: 937-954.

 

• Goodman LD, Cope H, Nil Z, Ravenscroft, TA, Charng WL, Lu S, Tien AC, Pfundt R, Koolen DA, Haaxma CA, … Moulton MJ, Dutta D, Kanca O, UDN Consortia, Wangler MF, Yamamoto S, Bellen HJ, Tan QKG (2021). De novo TNPO2 variants are associated with developmental delays, neurologic deficits and dysmorphic features in humans and alter TNPO2 activity in Drosophila. The American Journal of Human Genetics 108: 1669-1691.

 

2020

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• Dutta D*, Briere LC*, Kanca O, Marcogliese PC, Walker MA, High FA, Vanderver A, Krier J, Carmichael N, Callahan C, Taft RJ, Simons C, Helman G, Undiagnosed Diseases Network, Wangler MF, Yamamoto S, Sweetser DA, Bellen HJ (2020). De novo mutations in TOMM70, a receptor of the mitochondrial import translocase, cause neurological impairment. Human Molecular Genetics 29: 1568-1579. (*Co-first author) 

 

• Dutta D, Mutsuddi M, Mukherjee A (2020). Regulation of Notch Signaling in Drosophila melanogaster: The Role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex. Notch Signaling in  Embryology and Cancer, Advances in Experimental Medicine and Biology (Springer Nature) 1227: 95-105.

 

2019

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• Dutta D, Mutsuddi M, Mukherjee A (2019). Synergistic interaction of Deltex and Hrp48 leads to JNK activation. Cell Biology International 43: 350-357.

 

• Singh A, Paul MS, Dutta D, Mutsuddi M, Mukherjee A (2019). Regulation of Notch signaling by a chromatin modeling protein Hat-trick. Development 146: dev170837.

 

2018

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• Dutta D, Singh A, Paul MS, Sharma V, Mutsuddi M, Mukherjee A (2018). Deltex interacts with Eiger and consequently influences the cell death in Drosophila melanogaster. Cellular Signalling 49: 17- 29.

 

• Singh A, Dutta D, Paul MS, Verma D, Mutsuddi M, Mukherjee A (2018). Pleiotropic functions of chromo-domain containing protein Hat-trick during oogenesis in Drosophila melanogaster. G3: Genes, Genomes, Genetics 8: 1067-1077.

 

• Paul MS, Dutta D, Singh A, Mutsuddi M, Mukherjee A (2018). Regulation of Notch signaling in the developing Drosophila eye by a T-box containing transcription factor Dorsocross. Genesis 56: e23251.

 

• Paul MS, Singh A, Dutta D, Mutsuddi M, Mukherjee A (2018). Notch signals modulate lgl mediated tumorigenesis by the activation of JNK signaling. BMC Research Notes 11: 247.

 

2017

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• Dutta D, Paul MS, Singh A, Mutsuddi M, Mukherjee A (2017). Regulation of Notch signaling by the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex in Drosophila melanogaster. GENETICS 206: 905-918.